Enzymes are biological molecules (typically proteins) that significantly speed up the rate of virtually all of the chemical reactions that take place within cells.; they are catalysts which accelerate bodily chemical reactions. Digestive enzymes are proteins that break down larger molecules like fats, proteins and carbs into smaller molecules that are easier to absorb across the small intestine. Without sufficient digestive enzymes, the body is unable to digest food particles properly, which may lead to food intolerances. Digestive enzymes of diverse specificities are found in the saliva secreted by the salivary glands, in the secretions of cells lining the stomach, in the pancreatic juice secreted by pancreatic exocrine cells, and in the secretions of cells lining the small and large intestines. Lipases split fatty acids from fats and oils. Proteases and peptidases split proteins into small peptides and amino acids. Amylases split carbohydrates such as starch and sugars into simple sugars such as glucose. Nucleases split nucleic acids into nucleotides. The word “systemic” means body wide. Systemic enzymes not only aid digestion but also support bodily functions in every tissue and organ. These functions include defence against inflammation, fighting infection, modulating the immune system and cleansing the blood of cellular waste and fibrin – a hard, sticky protein formed during clotting of blood. Nearly every process in the human body involves chemical reactions catalysed by proteins called enzymes. They also serve as excellent prophylactic supplements for general body support.