Folic acid, the most common form of folate in supplements and fortified foods, requires the enzyme methylenetetrahydrofolate reductase (MTHFR) to be converted to L-methylfolate, the activated form of folate used by the body for many biochemical reactions.

About half of the population have genetic variations that reduce the ability of the MTHFR enzyme to make this conversion.

For this population, L-methylfolate supplementation is far more effective in providing this form of folate.

L-methylfolate, calcium salt (Extrafolate S®, Gnosis Bio, Italy) and glycine are made by chemical synthesis.

Dairy Free, Egg Free, Gluten Free, Nut Free, Vegan

Store in a cool, dark place out of reach of children

Food supplements should not be used as a substitute for a varied diet. If you are taking prescribed medication, have any medical condition, or are pregnant or breastfeeding, please consult your healthcare practitioner before taking food supplements.