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Omega-3s During Pregnancy

Omega-3s During Pregnancy: Supporting Mom and Baby

Omega 3 pregnancy supplementation can lower preterm birth risks by 42% with the right dosage. Many pregnant women in the UK barely eat any fish, which means they miss out on these vital nutrients.

DHA, a specific omega-3 fatty acid, helps develop your baby’s brain and retina. You can get this through fish oil supplements or by eating 8 to 12 ounces of low-mercury fish every week. Your baby’s brain grows the most during the third trimester, so getting enough DHA becomes even more significant at this time.

This detailed guide will help expectant mothers understand everything about omega-3s during pregnancy. You’ll learn about natural sources and supplement options that support both your health and your baby’s development.

Understanding Omega-3s in Pregnancy

Essential fatty acids are the foundations of life. They play vital roles in oxygen transport, energy storage, and cell membrane function. Our bodies can’t produce these nutrients, so we must get them from food [1].

What are omega-3 fatty acids?

Omega-3 fatty acids belong to a family of essential fats that work among omega-6 fatty acids to regulate inflammation and cell growth. α-linolenic acid (ALA) leads the omega-3 family and changes into biologically active forms inside our body [1]. These fatty acids build vital parts of cell membranes, especially in the brain and retina, where they support our vision and neural functions [1].

Why they matter for pregnancy

Omega-3s become even more important during pregnancy. The foetus gets these fatty acids mainly through the placenta [1]. Research shows that when mothers take omega-3 supplements, both they and their babies have higher DHA levels [2].

DHA builds up faster in the baby’s brain during the third trimester compared to other fatty acids [2]. On top of that, omega-3s protect the placenta through their anti-oxidative and anti-inflammatory properties [2].

Clinical evidence reveals these benefits of getting enough omega-3s:  

  • The risk of preterm birth drops by 11% before 37 weeks [3]
  • Early preterm birth risk falls by 42% before 34 weeks [3]
  • Pregnancy length increases by 1.67 days on average [3]

Key types: DHA and EPA

Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are the most powerful forms of omega-3s [1]. We get these fatty acids mainly from seafood and algae[1].

DHA makes up about 80% of all polyunsaturated fatty acids in the retina and 60% of the brain’s dry weight [2]. During foetal growth, DHA has several key roles:  

  • It builds crucial structures in brain cell membranes
  • Controls gene expression and neurotransmission  
  • Helps cell signalling processes [2]

EPA works with DHA to offer more benefits. These fatty acids fight against inflammatory compounds to reduce inflammation throughout the body [2]. EPA also helps create anti-inflammatory substances that benefit both mother and baby [2].

Despite their importance, 64% of countries worldwide consume less than 200 mg of DHA daily [2]. Pregnant women in the United States eat only 50 grammes offish weekly, and 10-20% don’t eat any fish [2]. Swedish pregnant women eat much more – about 184 grammes of seafood every week [2].

Our bodies struggle to turn plant-based ALA into EPA and DHA [2]. Getting these vital nutrients directly from food or supplements is essential to keep both mother and baby healthy.

Benefits for Baby’s Development

Foetal brain development starts early, and DHA plays a key role in building cognitive abilities. Studies show DHA makes up about 15% of all fatty acids in the human frontal cortex [4].

Brain growth and function

The foetal brain continuously accumulates DHA throughout pregnancy. The most active period runs from week 29 to week 40 [4]. During this vital stage, the brain accumulates DHA faster than other fatty acids [3].

DHA performs several key functions in brain development:  

  • Supports neurogenesis and neurotransmitter function  
  • Improves synaptic plasticity and signal transmission
  • Regulates cortical astrocyte maturation [4]

Babies whose mothers took 600 mg daily DHA supplements early in pregnancy showed better problem-solving skills at 9 months [3]. These benefits last beyond infancy, as higher DHA levels in cord blood relate to better hand-eye coordination [3].

Eye development

The retina, which extends from the brain, needs DHA to develop properly. DHA makes up about 80% of all polyunsaturated fatty acids in the retina [3]. This high concentration shows its vital role in visual development.

Research shows clear improvements in visual outcomes:

  • Mothers who took 600 mg daily DHA supplements had newborns with much better visual acuity [4]
  • A mother’s DHA levels directly affect her child’s visual development [4]

Nervous system support

DHA shapes nervous system development by influencing neuronal growth and connectivity. Research reveals DHA’s effects on neural development:

DHA helps maintain proper neuron size, which helps brain function work well [3]. A mother’s omega-3 levels affect neurogenesis, and low levels might affect cognitive function later [3].

DHA supports nervous system development in several ways:  

  • Keeps neural cell membranes fluid
  • Controls neurotransmission systems  
  • Helps myelination processes [5]

Research shows DHA builds up faster in retinal and brain neural tissue during pregnancy’s last three months [4]. This time window matters most for nervous system development. DHA seems to protect against pregnancy complications that could affect long-term neurodevelopment [4].

Low DHA levels during pregnancy can lead to:  

  • Changes in behaviour patterns
  • Learning difficulties
  • Memory-related challenges [4]

The third trimester needs special attention. Foetuses need about 40 to 60 mg of omega-3s per kilogramme of body weight each day [5]. This increased need matches significant brain growth and higher cerebral DHA levels [5].

DHA benefits continue past pregnancy. Good DHA supplements during pregnancy and breastfeeding boost DHA levels in infant tissues and lead to better neurological development [4]. Low omega-3 diets during pregnancy might hurt a child’s visual and neurological development [4].

New studies show DHA concentrates in the central nervous system and serves as the brain’s main fatty acid [6]. This concentration reaches its peak during the last trimester, right when the foetal brain grows fastest [6]. Understanding this timing helps ensure proper supplementation at the right time.

Benefits for Maternal Health

Omega-3 fatty acid levels in mothers substantially affect pregnancy outcomes. Research shows these nutrients play a vital role in both physical and mental health. Scientific evidence proves that omega-3s support everything in maternal health throughout pregnancy.

Reducing preterm birth risk

Preterm birth causes nearly one million infant deaths worldwide each year [4]. Notwithstanding that, research shows increased omega-3 intake during pregnancy helps protect against early delivery.

The largest longitudinal study of 70 randomised trials found remarkable results:  

  • Lowers premature birth risk (before 37 weeks) by 11% [4]
  • Cuts early preterm birth risk (before 34 weeks) by 42% [4]
  • Adds 107 grammes to average birth weight [3]

Pregnant women should take 600-1000 mg DHA+EPA daily to get the best results. They need to start by week 20 of pregnancy [4]. This supplement helps women with low DHA levels the most and should continue until week 37 or childbirth [4].

Women who consume less than 150 mg of omega-3 fatty acids daily face the highest risk of premature delivery [3]. Babies with DHA levels in the highest quarter of cord blood stayed in the womb 9.3 days longer than those in the lowest quarter [3].

Supporting mental wellbeing

Mental health issues during pregnancy can affect both mother and baby outcomes. Depression during pregnancy often leads to poor outcomes, while postpartum depression affects both the mother’s mental health and baby’s development [2].

Research reveals key findings about omega-3s and maternal mental health:

Omega-3 fatty acids are vital for brain structure and function [7]. These nutrients affect neurotransmitter systems and help control mood-related chemicals, especially serotonin [2].

The brain accumulates substantial amounts of DHA during pregnancy and breastfeeding, which increases physical demands [2]. A study found that countries with higher seafood consumption had lower rates of postpartum depression [7].

  • Clinical evidence shows these benefits from omega-3 supplements:  
  • Lower depressive symptoms in perinatal women [1]
  • Moderate benefits through anti-inflammatory properties [1]
  • Safe dosages from 1 to 6 grammes daily [1]

The International Society for Nutritional Psychiatry Research suggests:  

  • Pure EPA or EPA/DHA mix with a ratio above 2
  •  1-2 grammes net EPA daily
  •  Regular checks for side effects [1]

Higher omega-6 levels and elevated omega-6/omega-3 ratios relate to increased risk of perinatal depression [1]. Therefore, proper omega-3 levels are significant since these fatty acids stored during pregnancy serve vital functions in both mother’s and baby’s health [2].

Mild digestive issues might occur, but most side effects don’t last long [1]. Omega-3 supplements help especially when you have marked dietary deficiency or underlying inflammatory conditions [1].

Evidence proves that enough omega-3 intake supports both physical and mental aspects of maternal health. Many pregnant women risk low PUFA status due to increased needs [7]. This makes proper supplementation vital for the best pregnancy outcomes.

Natural Sources of Omega-3

Getting enough omega-3 fatty acids from your diet needs careful food choices. Pregnant women need to know their safe sources to meet daily needs and avoid risks.

Safe fish options

Oily fish is the best dietary source of omega-3 fatty acids. The NHS says you should eat at least two portions of fish every week, and one should be oily fish [8]. Here are your safe options:

  • Salmon
  • Sardines  
  • Herring
  • Freshwater trout  
  • Pacific mackerel  
  • Anchovies

These smaller oily fish pack plenty of omega-3s but keep mercury levels low [9]. Pregnant women should try to eat 8 to 12 ounces (about 226-340 grammes) of low- mercury fish each week [10].

You can also safely eat these seafood options:  

  • Shrimp
  • Pollock
  • Tilapia  
  • Cod
  • Catfish
  • Canned light tuna

When it comes to tuna, pregnant women shouldn’t eat more than four cans weekly or two tuna steaks because of higher mercury levels [8]. Canned tuna is usually safer throughout pregnancy since it comes from smaller fish and has less fish oils [9].

Plant-based sources

Marine sources give you the most readily available EPA and DHA, but some plant-based options provide alpha-linolenic acid (ALA). Your body isn’t great at converting ALA to EPA and DHA – less than 15% makes it through [11]. Still, these sources help with your overall omega-3 intake:

Flaxseed oil leads the pack among plant sources with 57% omega-3 fatty acids [3]. Canola oil follows with 11% omega-3s, and soybean oil contains 8% [3]. More plant-based sources include:

  • Walnuts and walnut oil  
  • Dark leafy greens
  • Brussels sprouts  
  • Chia seeds
  • Seaweed  
  • Edamame

Research shows plant-based sources alone won’t cut it. You’d need too many fat calories to get enough omega-3s just from vegetable oils [3]. Pregnant women who follow plant-based diets might need supplements to meet their daily needs.

Foods to avoid

Some fish are completely off-limits during pregnancy because of high mercury:

Shark, swordfish, and marlin should stay off your plate [8]. These big predatory fish build up mercury levels that could harm your baby’s nervous system development [8].

Watch out for these preparation methods too:

  • Raw fish might have parasites unless it’s properly frozen first [9]
  • Hot-smoked mackerel and salmon need to be cooked well [12]
  • Skip cod liver oil as an omega-3 source – it has too much vitamin A [6]

Some plant oils can mess with EPA absorption. Cottonseed, corn, and sunflower seed oils are high in omega-6s that compete with EPA [11]. It’s better to use flaxseed, canola, or soybean oil instead.

Most pregnant women struggle to get enough omega-3s from food alone [3]. Even if you eat two servings of low-mercury fish weekly and use omega-3-rich vegetable oils, you’ll likely fall short of the recommended 650mg daily intake (including 300mg of DHA) [3]. Many doctors suggest taking supplements to fill this gap.

Choosing Omega-3 Supplements

You need to think over many factors when choosing omega-3 supplements, from the type to quality markers. A good understanding of these elements will give you the best benefits for both mother and baby’s health.

Types available

Pregnant women can choose from several omega-3 supplement options that fall into two main categories. Fish oil supplements lead the pack as the most popular choice. They contain both EPA and DHA in different amounts [4]. These supplements typically deliver one-third to one-half of their total content as omega-3 fatty acids [3].

Algae-derived DHA supplements make a great alternative for women who follow plant-based diets. These supplements come from Crypthecodinium cohnii algae strain and go through strict manufacturing controls in FDA-inspected facilities [3]. Both fish oil and algae-based supplements work equally well to boost maternal DHA levels [5].

Krill oil supplements, which come from tiny shrimp-like sea creatures, offer another option beyond traditional fish oil [6]. Whatever supplement type you choose, stay away from cod liver oil supplements during pregnancy. They contain vitamin A levels that could be harmful [13].

Quality markers

Look for these quality indicators when picking omega-3 supplements:  

  • Mercury content verification
  • Third-party testing certification  
  • Oxidation level assessment
  • DHA concentration confirmation

Studies show big differences in supplement quality between manufacturers [14]. Right now, no omega-3 supplements have specific licences for pregnancy use [4]. This makes it vital to pick supplements from trusted manufacturers.

Pregnant women need at least 200mg of DHA daily, more than the standard adult recommendation of 250mg DHA and EPA combined [15]. Most prenatal supplements don’t have enough omega-3s – only one in six hits the mark [14].

When to start supplementing

The timing of omega-3 supplementation matters a lot. Research shows starting about six months before conception lets your body build up essential fatty acid stores [15]. This preparation helps since brain and nervous system development starts early in the embryo [15].

Women who are already pregnant should:  

  • Start by 12 weeks of pregnancy [16]
  • Keep going until 37 weeks gestation [17]
  • Stop after giving birth [4]

Daily intake recommendations change based on your situation:  

Standard amount: 500mg DHA daily [4]

 Maximum benefit: 1000mg DHA plus EPA daily [4]

 Higher amounts (600-1000mg) if you have low DHA blood levels [17]

Keep taking your regular pregnancy vitamins with omega-3 supplementation, as long as these vitamins don’t already have omega-3s [4]. This gives you complete nutritional support throughout pregnancy.

Getting enough omega-3s through diet alone can be tough [4]. In fact, to get 500mg of DHA from salmon, you would need:  Two large servings (150g) weekly [4]

 Three smaller servings (100g) weekly [4]

Talk to your healthcare provider before starting any supplements [6]. This step becomes extra important since many prenatal vitamins already contain DHA, usually between 200 to 300mg [6].

Safe Dosage Guidelines

Omega-3 supplementation throughout pregnancy needs the right dosage to give you the best benefits safely. Research shows clear guidelines about how much to take and when.

Recommended daily intake

Experts recommend different omega-3 levels based on your specific situation. Women who might get pregnant should take 250mg of DHA and EPA daily [17]. The amount goes up a lot once pregnancy is confirmed.

The Food and Agriculture Organisation says pregnant women should take at least 200mg DHA daily, which adds up to 300mg when combined with EPA [5]. Research shows higher doses can help women with low DHA blood levels even more.

Key dosage recommendations include:

 Standard daily intake: 500mg DHA plus EPA [4]

 Maximum beneficial intake: 1000mg DHA plus EPA combined [4]

 Minimum requirement: 200-250mg DHA specifically [18]

Taking more than 1000mg of combined DHA and EPA daily won’t give you extra benefits [4]. Women with low DHA levels get the best results from 600-1000mg daily [17].

Your body’s need for these essential fatty acids changes throughout pregnancy. The third trimester is when you’ll need them most, as your baby’s brain develops rapidly [3]. Your baby needs about 40-60mg of omega-3s per kilogramme of body weight each day at this stage.

Timing considerations

The right time to start and how long you take omega-3 supplements makes a big difference. Starting around 12 weeks of pregnancy works best [4]. This matches important development stages and helps both mom and baby the most.

Here are the vital timing factors:

You should start no later than the second trimester [17]. Starting before 20 weeks helps prevent premature birth more effectively [19]. The best schedule looks like this:

  •  Starting point: 12 weeks of pregnancy [4]
  •  Continuation: Until 37 weeks gestation [17]
  •  Cessation: After childbirth [4]

Taking supplements regularly throughout pregnancy works best. Studies of doses from 133 milligrammes to 3 grammes show that 2.7 grammes of combined EPA and DHA daily helps most women [1].

Side effects are usually mild, with some women noticing an odd taste [1]. These don’t last long and rarely stop women from taking their supplements.

Women taking prenatal vitamins should know that most don’t have enough omega-3s [4]. You’ll likely need separate omega-3 supplements even with your prenatal vitamins.

Food alone rarely provides enough omega-3s. You’d need to eat 300 grammes of cooked salmon to match typical supplement levels [1]. That’s too much fish, especially during pregnancy when you should limit fish intake.

The right omega-3 levels during pregnancy depend on proper dosage and timing. Regular check-ins with your healthcare provider will help you get the right amount, especially if you have specific risk factors or dietary restrictions. This personal approach helps you get the best results safely throughout your pregnancy.

Conclusion

Research shows omega-3 fatty acids are crucial during pregnancy. These nutrients support a mother’s health and her baby’s development. Studies confirm that proper DHA levels substantially lower the risks of preterm birth and help babies develop better brains and vision.

Fish and plants naturally contain omega-3s. Most pregnant women just need more than what their diet provides. Supplements are a great way to get the right amount. Studies suggest taking 200-1000mg DHA daily, based on personal needs.

The right timing matters as much as the proper dosage. Women should start taking omega-3s before getting pregnant or in their first trimester. This helps build up essential fatty acids at the time when the baby’s development needs them most.

Pregnant women should think over their omega-3 sources carefully. They can get these nutrients through food or supplements. Quality matters – supplements from trusted manufacturers with third-party testing ensure safety during pregnancy. A healthcare provider can help determine the right dose and schedule that works best.

Research keeps showing more benefits of omega-3s during pregnancy. Mothers who maintain good omega-3 levels give their babies better brain development, sharper vision, and improved health outcomes.

FAQs

Q1. How do omega-3 fatty acids benefit pregnancy?

Omega-3 fatty acids are crucial during pregnancy, supporting foetal brain and eye development. They may also help reduce the risk of preterm birth and aid in preventing perinatal depression in mothers.

Q2. When is omega-3 most important during pregnancy?

Omega-3, particularly DHA, is most critical during the third trimester of pregnancy. This period coincides with rapid foetal brain growth, where DHA plays a vital role in brain and retina development.

Q3. Can I take omega-3 supplements alongside my prenatal vitamins?

Yes, you can take omega-3 supplements alongside prenatal vitamins. However, it’s essential to consult your healthcare provider first, as some prenatal vitamins may already contain omega-3s. They can help determine the appropriate dosage based on your individual needs.

Q4. What are the best sources of omega-3 for pregnant women?

The best sources of omega-3 for pregnant women include low-mercury fish like salmon, sardines, and trout. For those who don’t consume fish, algae-based supplements are a good alternative. Plant sources like flaxseed and chia seeds also provide omega-3s, but in a less efficient form.

Q5. How much omega-3 should I take during pregnancy?

The recommended daily intake of omega-3 during pregnancy varies, but generally ranges from 200- 1000mg of DHA. Most experts suggest aiming for at least 300mg of combined DHA and EPA daily. It’s best to start supplementation early in pregnancy and continue until birth, under the guidance of a healthcare professional.

References

  1. https://www.who.int/tools/elena/bbc/fish-oil-pregnancy
  2. –   https://www.sciencedirect.com/science/article/abs/pii/S0165032717320141
  3. https://pmc.ncbi.nlm.nih.gov/articles/PMC2621042/
  4. –  https://www.liverpoolwomens.nhs.uk/media/2884/omega-3-for-women-attending-the-preterm-birth-prevention-clinic-mat_2019-227-v1.pdf
  5. –  https://www.ajogmfm.org/article/S2589-9333(23)00393-2/fulltext
  6. –  https://www.whattoexpect.com/pregnancy/your-health/omega-3-fish-oil-during-pregnancy
  7. https://pmc.ncbi.nlm.nih.gov/articles/PMC2667651/
  8. –  https://www.nhs.uk/live-well/eat-well/food-types/fish-and-shellfish-nutrition/
  9. –  https://www.london-gynaecology.com/what-fish-can-you-eat-when-pregnant/
  10. –  https://www.mayoclinic.org/healthy-lifestyle/pregnancy-week-by-week/in-depth/pregnancy-and-fish/art-20044185
  11. –  https://vegankidsnutrition.com/blog/vegan-omega3-in-pregnancy-and-breastfeeding
  12. –  https://www.bbc.co.uk/food/articles/what_you_should_and_shouldnt_eat_in_pregnancy
  13. https://www.aptaclub.co.uk/pregnancy/diet-and-nutrition/key-vitamins-and-nutrients/understanding-lcps.html? srsltid=AfmBOoqzVlNRsVRYcmBHsDoM9a5QbEvh8MPj0e2gSltENCRa2vgtZx0M
  14. https://theconversation.com/prenatal-supplements-largely-lack-the-recommended-amount-of-omega-3-fatty-acids-to-help-prevent-preterm-birth-new-research-244231
  15. –  https://www.barebiology.com/pages/guide-omega-3-fish-oil-pregnancy
  16. –  https://www.plymouthhospitals.nhs.uk/display-pil/pil-omega-3-omacor-supplements-6034/
  17. –  https://www.efcni.org/news/omega-3-nutrition-recommendations-preventing-ptb/
  18. https://pmc.ncbi.nlm.nih.gov/articles/PMC3046737/
  19. –  https://www.babycentre.co.uk/x541094/is-it-safe-to-take-fish-oil-supplements-in-pregnancy

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