Trustpilot 
Author is Jason Miller – Natura.
Enhancing longevity includes extending both lifespans, as well as “healthspan,” which, beyond number of years lived, equates to years lived in optimal health. Our wholistic approach to longevity is based on slowing the biological processes that drive aging, rather than waiting for the symptoms of disease to arise.
We use general protocols for promoting longevity while also addressing specific conditions with more targeted formulas.
Some of the most common chronic diseases associated with aging include:
- Cardiovascular disease
- High blood pressure
- Altered lipid metabolism
- Cancer
- Chronic kidney disease [CKD]
- Chronic obstructive pulmonary disease [COPD]
- Depression
- Dementia
- Diabetes
- Obesity
- Stroke
Adaptogens
The use of adaptogens is one of the fundamental strategies for promoting long lasting, systemic overall health. By enhancing the adaptive capacity of the body to effectively deal with the multitude of stressors that we face throughout our lives, adaptogens promote longevity and preserve healthspan. In addition, using a combination of anabolic enhancing botanical compounds with essential nutritional agents to create a synergistic and comprehensive approach.
Hallmarks of Aging
- Genomic instability
- Telomere attrition
- Epigenetic alterations
- Loss of proteostasis
- Deregulated nutrient sensing
- Mitochondrial dysfunction
- Cellular senescence
- Stem cell exhaustion
- Altered intercellular communication
- One common denominator of aging is the accumulation of genetic damage throughout life
Key Aging Factors
- Quenching network deficiency – “Essence”
- Declining anabolic hormones
- Hormonal dysfunction
- Reduced capacity to neutralize free radicals
- Increased levels of waste byproducts (eg. ROS)
- Inability to control inflammation (eg.TNF-a, IL-6)
- Immune function decline
- Reduced digestion/assimilation
- Reduced ability to utilize food for energy
- Depressed enzyme activity
- Increased levels of fatigue and longer time to recover
Loss of anabolic/catabolic balance
Aging is associated with reduced anabolic hormone activity including growth hormone, thyroid hormone and sex steroid axis activity with increased abdominal fat (insulin resistance). Lean mass contains the body’s protein content. Every protein molecule has a role in maintaining body homeostasis. Loss of any body protein is deleterious. Protein is responsible for the metabolic activity and body structure essential for survival. Protein synthesis is also essential for any tissue repair.
“Inflammaging”
In the elderly, hyperstimulation of the immune system results in a chronic, low-grade state of inflammation. Inflammaging is macrophage centered, involves several tissues and organs, including the gut microbiota, and is characterized by a complex balance between pro- and anti-inflammatory responses. The major source of inflammatory stimuli is represented by endogenous/self, misplaced, or altered molecules resulting from damaged and/or dead cells and organelles (cell debris), recognized by receptors of the innate immune system. While their production is physiological and increases with age, their disposal by the proteasome via autophagy and/or mitophagy progressively declines.
Loss of control of the ‘autoreactive/autoimmune’ process fuels the onset or progression of chronic diseases that can accelerate and propagate the aging process locally and systemically. Consequently, inflammaging can be considered a major target for antiaging strategies, and includes decreased microbiota diversity and stability, along with misfolded proteins spreading along the gut-brain axis.
Oxidative Stress and Mitochondrial Dysfunction
Unmanaged oxidative stress and impaired cellular stress responses are also central to aging. Current research reveals that rather than applying high dose anti-oxidants, the emphasis should be on consuming compounds that activate endogenous defense pathways. Natura’s botanical and nutritional medicine toolboxes are replete with tools that serve this purpose beautifully.
Environmental Toxins
Fortunately, the body has myriad ways of dealing with harmful compounds, including redox-anti-oxidant enzymes that break down large harmful chemical compounds into smaller compounds that are less damaging. These secondary oxidative compounds are then transported out of the body through the organs of elimination. However, our bodies were not designed for the large number of toxins we now encounter on a daily basis. Providing support for the organs of elimination through natural compounds such as those found in adaptogenic formulations aid in toxin removal without adding unnecessary stress to the body
Protocols for Supporting Aging Systems
Base Protocol
- Vital Adapt
- Power Adapt
- Amino Whey Pro Advantage
- N-Liven
- Night Gain
- Botanabol
- Mito-Gevity
CVD Specific
- Cardio Tonic BP
- Cho Less
- Complete Omega Essentials
- IG Sensitizer
- Vibrant Mind
Inflammation/Pain/Loss of catabolic control
- Inflamaway
- Botanical Treasures
- Willow Relief
Key Nutrition
- Dual Mag
- Zinc
- Vitamin DAK
- Iron Synergy
- N-Liven
Hormone Deficiency
- Menobreeze
- Botanabol
- Night Gain
Mental/Mood Health
- Up-Lift
- Tranquility
- Vibrant Mind
Bioremediation/Immune System Regulation
- Mushroom Synergy
- Immucare
- Adaptogens